Friday, May 14, 2004

08:15

Registration, put up posters

09:00

Opening ceremony

Antiinflammatory activity

Chair: Kerstin Danker (Berlin), Rudolf Tauber (Berlin)

09:15

Thomas Ruzicka (Düsseldorf)
New molecular targets in inflammatory skin diseases

10:00

Konrad Sandhoff (Bonn)
Sphingolipids as functional components of cell membranes and of the epidermal barrier for water

10:45

Dieter Steinhilber (Frankfurt/M.)
Mechanism of induction of 5-lipoxygenase gene expression by 1,25-dihydroxyvitamin D3 and transforming growth factor- beta

11:30

Coffee Break

11:50

Dietmar Vestweber (Münster)
Molecular mechanisms controlling endothelial permeability and leukocyte extravasation

12:35

Josef M. Pfeilschifter (Frankfurt/M.)
Matrix-metabolizing enzymes as prime targets of redox regulation by nitric oxide

13:20

Lunch

Interaction with membranes and natural barriers

Chair: Oliver Liesenfeld (Berlin), Beate Röder (Berlin)

14:30

Hans E. Junginger, J. Coos Verhoef (Leiden)
Novel carriers for peroral peptide delivery and absorption

15:15

Britta Engelhardt (Münster)
Molecular mechanisms of T Cell migration across the blood-brain barrier in vitro and in vivo

16:00

Alfred Blume (Halle)
Interactions of polar and amphipathic molecules with lipid model membranes

16:45

Sven Krüger (Berlin)
Application of addressable light patterns to gather information of cellular systems

18:00

Boat tour

Saturday, May 15, 2004

Influencing hyperproliferative and fibrotic diseases

Chair: Ronald Gust (Berlin), Werner Reutter (Berlin)

09:00

Gert Fricker (Heidelberg)
Taxol - new therapeutic options for the treatment of brain tumors

09:45

Horst Kunz (Mainz)
Synthetic glycopeptides - candidates for the development of antiinflammatory and antitumor drugs

10:30

Hans Merk (Aachen)
Chemoprevention of skin cancer - from xenobiotica metabolism to new drug targets

11:15

Coffee Break

11:35

Rolf W. Hartmann (Saarbrücken)
Identification of a novel target (CYP11B2) for the treatment of cardial fibrosis and first drug discovery results

12:20

Anita Roberts (Bethesda, MD)
Inhibition of Smad3 - a novel therapeutic approach to prevention of fibrotic sequelae?

13:05

Closing ceremony

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